Estrella lausannensis and amoeba-resisting microorganisms: human exposure and potential pathogenicity
|Director of thesis||Gilbert Greub (IMUL|
|Co-director of thesis||Yves Lévi (Paris XI, France)|
|Summary of thesis||
The primary aim of the thesis is to evaluate human exposure to Chlamydiae, using a newly developed pan-Chlamydiae real-time PCR, immunofluorescence serological tests. Amoebal methods will be used to evaluate the presence of amoeba-resisting microorganisms, including Chlamydiae, in domestic water systems of patients.
Furthermore, the description of a recently described Chlamydia-related bacterium, Estrella lausannensis will be realized. The peculiar membrane of its star-shaped infectious forms will be studied using proteomic analyses.
|Administrative delay for the defence|