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Title

Implementation of PBPK (Physiologically Based PharmacoKinetic) modeling in clinical practice with the Virtual Twin approach

Author Jérémie MÜLLER
Director of thesis Prof. Caroline Samer
Co-director of thesis Prof. Youssef Daali
Summary of thesis

Improving PBPK modelling prediction by integrating Genomics, Proteomics and Phenotypic information in the models.

Using PBPK and Virtual Twin approach to individualize treatment in clinical care for Tacrolimus and Tamoxifen.

Status beginning
Administrative delay for the defence 2029
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