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Genetic interactions in Streptococcus pneumoniae

Author Julien DÉNÉRÉAZ
Director of thesis Jan-Willem Veening
Co-director of thesis
Summary of thesis

Streptococcus pneumoniae is an opportunistic human pathogen. With the raise of multi-drugs resistant strains, finding new antimicrobial targets is required. To discover new synthetic lethal genes which could be used for combinatorial therapies, a synthetic lethal screen was performed using a CRISPR interference library targeting all operons in different genetic backgrounds of Streptococcus pneumoniae D39V.

Status beginning
Administrative delay for the defence 2024
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