Detailed information about the course

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GWAS and Beyond


September 30 & October 1st, 2021

Lang EN Workshop language is English

Prof. Sven Bergmann, UNIL


Prof. Sven Bergmann, UNIL

Prof. Olivier Delaneau, UNIL

Prof. Jacques Fellay, CHUV, Lausanne & EPFL

Prof. Zoltán Kutalik, UNIL


We will start with a quick introduction to Genome-wide association studies (GWAS), including data generation (genotyping/sequencing/imputation) and study design. After this we'd focus on more advanced topics, including fine-mapping of GWAS signals, Mendelian randomisation, GWAS with molecular traits, such as gene expression, epigenetics and metabolomics data, the mapping of association signal onto genes or pathways, and how association signal at different levels can be integrated. Participants are expected to have some coding experience (preferably in R and bash) and basic knowledge in statistics. The course will include both interactive presentations and hands-on sessions where real data will be analysed under our supervision.





Arrival & Coffee from 09:30


Thursday morning 10:30-12:00 (Sven Bergmann/Olivier Delaneau):

Quick introduction to Genome-wide association studies (GWAS), including data generation (genotyping/sequencing/imputation) and study design. Regression and other tests. Multiple Hypotheses testing, Manhattan and QQ plots etc.



Lunch break 12:00-13:30



Thursday early afternoon 13:30-14:30 (Zoltan Kutalik)

Heritability estimation.



Break 14:30-15:00



Thursday afternoon 15:00-16:30 (Olivier Delaneau)

Fine-mapping of GWAS signals, eQTL, integration of epigenetics.



Thursday late afternoon 17:00-18:00 (Sven Bergmann)

Mapping of association signal onto genes or pathways, network analysis.







Lunch break 12:00-13:00


Friday early afternoon 13:00-14:30 (Zoltan Kutalik)

Causality and Mendelian randomization.


Break 14:30-15:00


Friday late afternoon 15:00-16:30 (Jacques Fellay)

Translational aspects of GWAS: use of genetic variants in personalized medicine and epidemiology.


16:45: Joint discussion Quo vadis GWAS? / Feedback




Les Diablerets (VD)


To participate, the hotel requests that you present a COVID-pass (full vaccination) or a rapid antigen test (validity 48h at least).



Reimbursements for CUSO StarOmics students:
- Train ticket, 2°class, half-fare from your institution to the place of the activity.

NEW from 2021: Reimbursement of your travel tickets can be asked online through your MyCUSO. See HERE for the procedure.

For any question concerning reimbursement please contact the CUSO StarOmics coordinator

For cancellations after September 10 , participants will be charged with 100.- CHF of cancellation fee.



Deadline for registration 14.10.2021
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