[ANNULÉ] Swiss Institute of Statistical Genetics - Association Mapping: GWAS and Sequencing Data

Summer 2022

Prof. Jérôme Goudet, University of Lausanne (CH) & Swiss Institute of Bioinformatics

Prof. Timothy A. Thornton, University of Washington
Prof. Michael Wu, Fred Hutchinson Cancer Research Center, Seattle

This module will provide students with the basic tools to carry out genetic association analysis within the context of genome wide association studies (GWAS) and next-generation sequencing studies with considerable emphasis on hands-on learning. Topics covered include: case-control (disease) association testing; quantitative trait analysis; quality control processes in GWAS; multi-locus testing using gene and pathway information; population structure and ancestry inference; association testing in the presence of population structure and/or relatedness; gene-environment and gene-gene interactions; basic rare variant association analysis in sequencing studies; advanced rare variant methods; sequence kernel association tests (SKAT); meta analysis; design considerations; and other emerging topics. An important component of this module is in-class software exercises which will provide students with hands-on experience analyzing real data using state-of-the-art analysis tools for GWAS and next generation sequencing data

TBA

Lausanne

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