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| Title | Structure-function analysis of disaggregating chaperones in yeast |
| Author | Mathieu REBEAUD |
| Director of thesis | Prof. Pierre Goloubinoff |
| Co-director of thesis | |
| Summary of thesis | Specifically, I am working on the two disaggregase machineries that co-exist in the yeast cytosol, Hsp100/70 and Hsp104/70 and on their interactions with the J-domain proteins Sis1 and Ydj1 and various misfolded substrates. The goal is to better understand the functional and mechanistic differences between the two systems. |
| Status | finishing |
| Administrative delay for the defence | |
| URL | |