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| Title | Molecular basis of RIG-I activation |
| Author | Stéphanie ANCHISI |
| Director of thesis | Dominique GARCIN |
| Co-director of thesis | |
| Summary of thesis | My PhD project is anchored in innate immunity by focusing on the cytoplasmic receptor RIG-I, namely the conditions of its activation in relation to its ability to discriminate between self and non-self RNAs. For this purpose, we have studied the nucleotides involved in the different steps of RIG-I activation: binding, ATPase stimulation and ultimately IFNβ induction. |
| Status | |
| Administrative delay for the defence | |
| URL | |