NGS - Genome Variant Analysis (SIB)

June 11-12, 2026

Dr Valeria Di Cola Training Manager, SIB
Dr Diana Marek, SIB training group
Dr Sarah Miéville, CUSO Microbiology

TBC

The detection of genetic variation is of major interest in various disciplines spanning from ecology and evolution research to inherited disease discovery and precision oncology. Next generation sequencing (NGS) methods are very powerful for the detection of genomic variants. Thanks to its throughput and cost-efficiency it enables the detection of a large number of variants in a large number of samples. In this two-day course we will cover the steps from read alignment to variant calling and annotation. We will mainly focus on the detection of germline mutations by following the GATK best practices. The training materials for this course are in its dedicated GitHub page.

Learning objectives: At the end of the course participants should be able to:
- Understand important aspects of NGS and read alignment for variant analysis
- Perform a read alignment ready for variant analysis
- Perform variant calling according to GATK best practices
- Perform a variant annotation Prerequisite: This course is intended for life scientists who are already familiar with general concepts of NGS technologies and want to expand their knowledge and skills on variant analysis

Basel

• EE (4 places)
• Staromics (4 places)
• Microbiology (6 places)
• MPS (2 places)

Usually 2 months before the course on this link : https://www.sib.swiss/training/course/20260611_NGSGV
(Please register also on the CUSO website in order to claim your travel costs).

Registration deadline: 28 May 2026

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