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| Title | Identification and characterization of leukemia stem cells (LSCs) in pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL) using in vitro and in vivo models. |
| Author | Zaira LENI |
| Director of thesis | Dr. Alexandre Arcaro |
| Co-director of thesis | Dr.med.Kurt Leibundgut |
| Summary of thesis | The aim of the doctoral work is to identify the potential LSC (Leukemia Stem Cells) population by in vitro studies and an in vivo model using immunodeficient mice (NOD-scid IL2rg -/-). The overall goal is to develop a new understanding and treatment possibilities of cases that currently cannot be cured, such as BCP-ALL cases at relapse with high-risk features or poor eventual outcomes. |
| Status | |
| Administrative delay for the defence | June 2015 |
| URL | |