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Title

Healing of cartilage lesions in sheep after microfracturing technique and transcutaneous application of non-steroidal anti-inflammatory or chondroprotective medication

Author Michele SIDLER
Director of thesis Prof. Dr. Brigitte von Rechenberg
Co-director of thesis Prof. Dr. Klaus Siebenrock
Summary of thesis

We are testing a novel treatment concept of percutaneous application of anti-inflammatory substances into the joint. Therefore we are creating critical size defects in the weight bearing area of the medial femoral condyle in sheep. We include molecular biology and histological techniques to assess the up- resp. downregulation of the expression of inflammatory components within the joint and the stage of cartilage degeneration.

Status middle
Administrative delay for the defence début 2014 : michele.sidler@gmail.com
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