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Title

Antibiotic-induced disruption of the maternal and infant microbiota and adverse health outcomes

Author Tess BONATO
Director of thesis Petra Zimmermann
Co-director of thesis Laurent Falquet
Summary of thesis

In this prospective cohort study, we will use metagenomic sequencing to determine the effect of:

1) intraputum antibiotics on the composition of the breast milk, and the infant oral and intestinal microbiome (including the development and persistance of antibiotic resistance)

2) antibiotic exposure in the first year of life on the composition of the infant oral and intestinal microbiome (including the development and persistance of antibiotic resistance)

3) disruption of the infant oral and intestinal microbiome on health outcomes

4) We will also determine the compositional overlap between the maternal intestinal microbiome, the breast milk microbiome and the infant oral and intestinal microbiome.

Status beginning
Administrative delay for the defence 2024
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