Detailed information about the course

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Title

The Search for Selection

Dates

6-10 September 2021

Responsable de l'activité

Jérôme Goudet

Organizer(s)

Prof. Jérôme Goudet, UNIL

Speakers

Prof. Bruce Walsh, University of Arizona, US

Description

A vast number of approaches have been suggested in the search for selection, ranging from genomic‐based signatures of recent or ongoing selection, tests based on either excessive amounts or nonrandom patterns of divergence (in both fossil sequences and with functional genomics data) and the more classical Lande‐Arnold fitness estimates (direct association of phenotypic values with fitness estimates) and their modern extensions. This workshop presents an integrated overview of all these approaches.

Program

Program outline

Day 1: Tests of neutral trait divergence (WL Chapter 12)
Lecture 1: Drift in the mean of quantitative traits
Lecture 2: Rate-based and time-series based tests
Lecture 3: Qst vs Fst
Lecture 4: Orr QTL tests (and their extensions)

Day 2: Tests based on Molecular Data I (WL Chapters 8, 9)
Lecture 5: Sweep theory
Lecture 6: Genomewide signatures from repeated past selection
Lecture 7: Polymorphismbased tests 1: Allele frequency changes and Lewontin-Krakauer tests
Lecture 8: Polymorphismbased tests 2: Genome pattern-based tests and SFS tests

Day 3: Tests based on Molecular Data II (WL Chapters 9, 10)
Lecture 9: Polymorphism-based tests 3: Haplotypebased tests
Lecture 10: Polymorphismbased tests 4: Domestication genes and other examples
Lecture 11: Divergencebased tests 1: HKA and MK tests
Lecture 12: Divergencebased tests 2: Rate of adaptive substitutions, Poisson random field models

Day 4: Estimating Individual fitness (WL Chapter 29)
Lecture 13: Episodes of Selection and the Assignment of Fitness
Lecture 14: Variance in Individual Fitness, Bateman gradients

Trait-fitness associations I (WL Chapter 29)
Lecture 15: Descriptions of Phenotypic Selection 1: Basics
Lecture 16: Descriptions of Phenotypic Selection 2: Fitness surfaces

Day 5: Trait-fitness associations II (WL Chapter 30)
Lecture 17: Multivariate selection 1: Basics
Lecture 18: Multivariate selection 2: Fitness surfaces
Lecture 19: Multivariate selection 3: Elasticities, path analysis, levels of selection
Lecture 20: wrap up and conclusions

Location

University of Lausanne

Evaluation

Full attendance and active participation

Information

When?
September 6 to 10

Where?
University of Lausanne
Auditorium in Biophore, UNIL-Sorge

Questions?
Marta Bellone
@: ecologie-evolution@cuso.ch

Expenses

Reimbursement:

Travel expenses:

PhD students of the DPEE are eligible for the reimbursement of incurred travel expenses by train (half-fare card, and 2nd class).

The online reimbursement system is now in place, so once the course is over you will be able to request the reimbursement via MyCUSO, without sending the paperwork to me. More information: Reimbursement

Accommodation:

Please contact the coordinator of the doctoral program (ecologie-evolution(at)cuso.ch) BEFORE the beginning of the course. NO reimbursement of accommodation without the coordinator of the doctoral program agreement prior of the course. In case of overnight stay, please post the original tickets and original bills along with the reimbursement form to:

Marta Bellone
Département de Génétique et évolution - Unité d'anthropologie
Sciences II, 30 quai Ernest-Ansermet, 1205 Genève

NO reimbursement of meal expenses

Registration

Through your myCUSO account!

Registrations are now open!

Priority is given to PhD students of the DPEE until 15 August 2021. After this deadline, first comes, first serves! 

Registration Fees:

Free for participants enrolled in the CUSO Ecology & Evolution doctoral program.
In case of cancellations, before the deadline: free
Late cancellations or no-show: Administrative fee of 100 CHF will be demanded
Other participants: please contact the program coordinator at ecologie-evolution(at)cuso.ch

Places

20

Deadline for registration 22.08.2021
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