Detailed information about the course

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Title

The Search for Selection

Dates

7-11 September 2020

Organizer(s)

Prof. Jérôme Goudet, UNIL

 

Speakers

Prof. Bruce Walsh, University of Arizona, US

 

Description

A vast number of approaches have been suggested in the search for selection, ranging from genomicbased signatures of recent or ongoing selection, tests based on either excessive amounts or nonrandom patterns of divergence (in both fossil sequences and with functional genomics data) and the more classical LandeArnold fitness estimates (direct association of phenotypic values with fitness estimates) and their modern extensions. This workshop presents an integrated overview of all these approaches.

 

Program

Program outline

 

Day 1: Tests of neutral trait divergence (WL Chapter 12)

Lecture 1: Drift in the mean of quantitative traits

Lecture 2: Rate-based and time-series based tests

Lecture 3: Qst vs Fst

Lecture 4: Orr QTL tests (and their extensions)

 

Day 2: Tests based on Molecular Data I (WL Chapters 8, 9)

Lecture 5: Sweep theory

Lecture 6: Genomewide signatures from repeated past selection

Lecture 7: Polymorphismbased tests 1: Allele frequency changes and Lewontin-Krakauer tests

Lecture 8: Polymorphismbased tests 2: Genome pattern-based tests and SFS tests

 

Day 3: Tests based on Molecular Data II (WL Chapters 9, 10)

Lecture 9: Polymorphism-based tests 3: Haplotypebased tests

Lecture 10: Polymorphismbased tests 4: Domestication genes and other examples

Lecture 11: Divergencebased tests 1: HKA and MK tests

Lecture 12: Divergencebased tests 2: Rate of adaptive substitutions, Poisson random field models

 

Day 4: Estimating Individual fitness (WL Chapter 29)

Lecture 13: Episodes of Selection and the Assignment of Fitness

Lecture 14: Variance in Individual Fitness, Bateman gradients

 

Trait-fitness associations I (WL Chapter 29)

Lecture 15: Descriptions of Phenotypic Selection 1: Basics

Lecture 16: Descriptions of Phenotypic Selection 2: Fitness surfaces

 

Day 5: Trait-fitness associations II (WL Chapter 30)

Lecture 17: Multivariate selection 1: Basics

Lecture 18: Multivariate selection 2: Fitness surfaces

Lecture 19: Multivariate selection 3: Elasticities, path analysis, levels of selection

Lecture 20: wrap up and conclusions

 

Location

University of Lausanne

Credits

2.5 ECTS

Evaluation

Full attendance and active participation

 

Information

When?

7-11 September 2020

 

Where?

University of Lausanne

 

Questions?

Marta Bellone

@: ecologie-evolution@cuso.ch

 

Expenses
Reimbursement:

 

PhD students of the DPEE are eligible for reimbursement of incurred travel expenses by train (half-fare card, and 2nd class). Please send the original tickets along with the reimbursement form to:

 

 Marta Bellone 

 Doctoral Program in Ecology and Evolution

 University of Fribourg

 Chemin du Musée, 10

 CH-1700 Fribourg

 

NO reimbursement of your meal expenses

 

Regarding reimbursement of accommodation, please contact the coordinator of the doctoral program (ecologie-evolution(at)cuso.ch) BEFORE the beginning of the course. NO reimbursement of accommodation without the coordinator of the doctoral program agreement prior of the course.

 

Registration

Register via your MyCUSO account!

 

Priority is given to PhD students of the DPEE until August 9, 2020. After this deadline, first comes, first serves

 

Registration Fees: 

 

Free for participants enrolled in the CUSO Ecology & Evolution doctoral program.

 

In case of cancellations, before the deadline: free

Late cancellations or no-show: 100 CHF administrative fee

 

Other participants: please contact the program coordinator at ecologie-evolution(at)cuso.ch

 

Places

20

Deadline for registration 23.08.2020
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