Exploring common and rare disease genetics with GWAS and NGS

25-27 April 2016

Ioannis Xenarios

Brian Stevenson (SIB/Vital-IT)

Brian Stevenson (SIB/Vital-IT), Zoltan Kutalik (SIB/Statistical Genetics), Sylvain Pradervand (SIB/Vital-IT)

During these three days the lectures and practical sessions will be dedicated to the exome and complete genome analysis, the use of genetic-based data as well as variant identification in two domains, human genetics and cancer variation. A particular emphasis will be put on practical sessions.

UNIL, Génopode, Aud. 2020

Map

Overview

Participants will learn about the genome-wide analysis of variation including GWAS, next generation sequencing (NGS) and how to identify and interpret variants in exomes. The course will also introduce techniques to extend GWAS using NGS data. Furthermore, we strongly encourage you to attend the Symposium on Genomics that will take place just after the end of the course (28 April 2016) in Lausanne.

Program summary

Day 1: GWAS basics and advanced
Day 2: Exome sequencing: From DNA sample to variants file
Day 3: Variant annotation and prioritization

Learning objectives

After three days of lectures and practical exercises, participants should:

• have a clear understanding of genome variation
• be able to perform GWAS and exome analyses
• be able to apply these techniques in translational research.

Prerequisites

Knowledge / competencies: Participants should have a good understanding of command-line UNIX (UNIX Fundamentals self-learning module) in order to perform the practical exercises.
Technical: A WiFi-equipped laptop with 3-4GB of RAM, 60GB free hard-disk space and virtualbox installed. You will be given virtual machine images with all softwares and packages needed for this course. See also: sib.swiss

Free for members of StarOmics, CHF 150.- for academics. Other, please contact us.

CUSO PhD students: through your MyCUSO account. External participants (non-CUSO PhD students, post-docs, etc...): use the icon "registration" at top of page and the last gray box "non-CUSO student" ("personne hors myCUSO").

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